There's a browser window, with the URL what-if.xkcd.com. The title of the page, in big letters, says "What if?", and below that is an ad for the What if? book. The title of the specific article is "What if this isn't everything it should be?", and the question is "I'm not even sure how I feel. What if I'm making a mistake?"
Title text: I once made an anniversary card for my then-girlfriend with this layout.